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Development and validation of a stability indicating method for seven novel derivatives of lamivudine with anti-HIV and anti-HBV activity in simulated gastric and intestinal fluids
(Elsevier Science, 2013-02)
A simple micellar liquid chromatography (MLC) method has been developed and validated for use in stability indicating studies of lamivudine and its carbonate derivatives with proved activity against human immunodeficiency ...
Influence of dairy practices on the capacity of probiotic bacteria to overcome simulated gastric digestion
(Wiley, 2014-06)
The aim of this study was to evaluate the influence of microbiological and technological factors on the viability and functionality of probiotic Lactobacillus strains. In particular, the influence of harvesting time, food ...
Acidic and hepatic derivatives of bioactive clerodane diterpenes casearins J and O
(2019-09-01)
Clerodane diterpenes from Casearia sylvestris are antiulcerogenic and anti-inflammatory. The finding that they may undergo acid degradation or hepatic metabolization led to an investigation of their degradation products. ...
ASSESSMENT OF THE HYDROLYTIC DEGRADATION OF LOVASTATIN BY HPLC
(Sociedad Chilena de Química, 2005)
Controlled release of sulfasalazine release from "smart" pectin gel microspheres under physiological simulated fluids
(Springer, 2012-07)
Sulfasalazine (SLZ) is a synthetic nonsteroidal anti-inflammatory drug used mainly for the treatment of an inflammatory bowel and other diseases. Two pectins with different methylation degrees were blended to synthesized ...
Reduced food interaction and enhanced gastrointestinal tolerability of a new system based on risedronate complexed with Eudragit E100: Mechanistic approaches from in vitro and in vivo studies
(Elsevier Science, 2016-10)
Novel complexes consisting of Eudragit E100-risedronate are presented. The oral bioavailability of risedronate in rats was determined through its percentage excreted in urine after administration of complexed or free ...
Stability of an Aqueous Extract of Larrea divaricata Cav. during a Simulated Digestion Process
(John Wiley & Sons Ltd, 2017-11)
Larrea divaricata Cav. (Zygophyllaceae) is a South American plant widely distributed in Argentina that isused in folk medicine to treat inflammatory diseases. The aqueous extract is known to have well-documented biological ...